Faculty and Staff Biography

 

Nawaporn Sanguantrakun

Assistant Professor, Chemistry
Department of Basic Sciences
314.446.8479
 

Education

B.Sc. Department of Chemistry, Khon Kaen University, Khon Kaen, Thailand

M.S. Organic Chemistry Department of Chemistry and Biochemistry, California State University Fullerton

Ph.D. Organic Chemistry Department of Chemistry, Purdue University, West Lafayette

Postdoctoral Fellow Department of Chemistry and Petroleum Reservoir Group, Department of Geoscience, University of Calgary, Alberta, Canada

Specialty

  • Organic Synthesis
  • Natural Product Chemistry
  • Solid Phase Peptide Chemistry
  • Native Chemical Ligation
  • Protein Mass Spectrometry

Current Research

My research interests include Mass Spectrometry (MS) approach for Protein footprinting to determine changes in proteins resulting from binding (e.g., protein-protein or protein-drug interactions), aggregation, and various other perturbations. These changes can be probed by chemical reactions that occur more slowly when the region becomes less solvent-accessible. Fast photochemical oxidation of proteins (FPOP) is a MS-based protein footprinting method utilizes a pulsed laser to photolyze hydrogen peroxide to generate OH radicals and modify proteins in a flow system on the microsecond timescale. This research is in collaborating with NIH/NIIGMS Biomedical Mass spectrometry resource, Washington University, Chemistry Department. Current research project is focusing on design and development of new reagents and radicals besides OH radicals to be used in FPOP.

For students interested in research opportunities, please email: nawaporn.sanguantrakun@stlcop.edu to inquire.

Current Courses, Activities, and Scholarly Interest

Chemistry 1212, 2213, and 2314 lecture and laboratory.

About

Honorary Visiting Assistant Professor at Chemistry Department, Washington University (2015-present)