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Biography

JOHN BEALE,  Ph.D.

Professor, Medicinal Chemistry
jbeale@stlcop.edu
314.446.8461

Education

B.S., Pharmacy, University of Iowa
M.S. Medicinal Chemistry and Pharmacognosy, University of Iowa
Ph.D. Medicinal Chemistry and Pharmacognosy, Univ. of Iowa
Postdoctoral Fellowship, Bioorganic Chemistry, Ohio State University
Postdoctoral Fellowship, Chemistry, University of Washington


Area of Speciality
Medicinal Chemistry
Pharmacognosy
Computational Biology and Cheminformatics


Favorite courses,activities,and scholarly interest
Favorite Courses: Medicinal Chemistry 1 and 2
 
Scholarly Interests: I am conducting research on a brain protein that is named TDP-43. The protein misfolds under some conditions, and when it does so it causes Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) , Frontotemporal Lobar Degeneration (early onset dementia), and Alzerimer Disease. My work involves NMR studies to elucidate the three dimensional structure of the protein and computational studies to study the misfolding reaction. The computational studies involve molecular dynamics, and replica exchange molecular dynamics.


Vita highlights
Senior editor and author, Wilson and Gisvold's Textbook of Organic, Medicinal, and Pharmaceutical Chemistry, 11th and 12th editions.
 
2008-2009 Chair, AACP Section of Chemistry

About Me
Dr. Beale loves animals and has two cats and four parrots. His wife also is a pharmacist (psychiatric research), and they have two daughters. He enjoys playing the bass trombone in a band, photography, computers, and music.


 
 
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