St. Louis Medication Disposal

St. Louis Medication Disposal Initiative Permanent Medication Disposal Sites Safe Needle and Sharps Disposal

The next nationwide medication disposal day will be September 27, 2014. 

On Sept. 27, you can take your medication to temporary drop-off sites between 10 a.m. and 2 p.m.

The Drug Enforcement Administration maintains a list of locations which will accept medications on that day only. You can also use one of the permanent St. Louis area disposal locations listed in the map below.


  • Flyer to display in your pharmcy or hand to patients promoting Sept. 27 disposal date (PDF).
  • Printable tri-fold pamphlet with permanent St. Louis area medication disposal locations  color brochure (PDF).

Permanent St. Louis Area Medication Disposal Sites

Please call ahead to confirm site is still operational. Map last updated April, 2014.

Safe Needle and Sharps Disposal Information

Missouri does not currently have any designated drop off locations, so first ask your health care provider, pharmacy, hospital, or veterinarian if they will accept your sharps for disposal.

Sharps may be disposed of in regular trash after they have been packaged in rigid, leak-proof containers (e.g. detergent bottle, metal coffee can) and tightly sealed.

  • Tape a label with the words “Infectious Waste” or “Biohazard Waste” to the outside of the container.
  • Seal the container lid using as strong tape (e.g. duct tape) before placing in trash.
  • Contact your waste hauler to explain how you will be disposing of your sharps and confirm that they will accept. 

What not to do with these items:

  • Never place loose needles in the trash.
  • Never dispose of containers with used needles in a recycling bin.
  • Never flush sharps down the toilet.

Helpful Links


* Each day, 2,700 teenagers abuse a prescription drug for the first time. Protect your family. 



Every year in April, St. Louis College of Pharmacy, the City of St. Louis, and the U.S. Drug Enforcement Administration (DEA) partner to allow residents to drop-off expired and unused prescription and over-the-counter medications at sites throughout the region. 

Drop off locations in the city of St. Louis will be at the following Walgreens: (April disposal only)

4218 Lindell, St. Louis, MO 63108
3822 S. Kingshighway, St. Louis, MO 63109
1530 Lafayette, St. Louis, MO 63104
3720 N. Kingshighway, St. Louis, MO 63115

Since the partnership formed in 2011, more than 30,000 pounds of medication has been removed from homes and kept out of the groundwater and landfills.

To continue the success of the Medication Disposal Initiative year-round, the College partners with Missouri American Water, Metropolitan Sewer District, and the St. Louis County Police to create permanent disposal sites in St. Louis County. The group, Missouri Prescription Pill and Drug Disposal (P2D2), maintains several drop-off locations in the region. More locations are being added every year. Disposal location can be found here. Local police and sheriff’s departments may also operate disposal programs.

It may seem harmless to have old medication tucked away in a cabinet or drawer. The majority of abused prescription drugs are obtained from friends and family and often come from home medicine cabinets. The problem can’t be solved by throwing medications in the trash. Changing the location of these sometimes toxic medications does not change their accessibility. In fact, for those looking to abuse medications or for curious children and pets, the trash can be an ideal, unmonitored location. Flushing the medication down the toilet is also an issue because the water company does not screen for the medicine’s active ingredients meaning they can show up again in the water supply and the environment.

Learn more about how to dispose of medications safely by exploring our web resources below. Questions? E-mail